Journal of Pharmacy And Bioallied Sciences
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ORIGINAL/BRIEF
Year : 2012  |  Volume : 4  |  Issue : 5  |  Page : 10-11

Cartilage targeted chemical delivery of naproxen and ibuprofen for the treatment of arthritis


Department of Pharmacy, Faculty of Technology and Engineering, The M.S. University of Baroda, Vadodara, Gujarat, India

Correspondence Address:
Mange Ram Yadav
Department of Pharmacy, Faculty of Technology and Engineering, The M.S. University of Baroda, Vadodara, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7406.94119

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NSAIDs are among the most widely used prescription drugs, for the treatment of pain and inflammation, particularly arthritis. Inhibitor of COX and NSAIDs relieve the signs and symptoms of inflammation by decreasing PG production but may cause GI and renal damage. Synthesis, stability studies and Y-imaging studies are carried out. Cartilage targeting strategy for conventional NSAIDs has been explored for reducing their local and systemic side effect of the NSAIDs site specific delivery of quarternary ester derivatives could have to be an effective strategy for long term therapy of inflammatory conditions like arthritis.


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