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ORIGINAL/BRIEF
Year : 2012  |  Volume : 4  |  Issue : 5  |  Page : 33-34

Design and development of colon specific microspheres for chronotherapy of hypertension


1 Department of Pharmaceutics, L. B. Rao Institute of Pharmaceutical Education and Research, B. D. Rao College Campus, Bethak Road, Khambhat, Gujarat, India
2 Department of Pharmaceutics, S. M. B. T College of Pharmacy, Nasik, Maharastra, India

Correspondence Address:
P Patel
Department of Pharmaceutics, L. B. Rao Institute of Pharmaceutical Education and Research, B. D. Rao College Campus, Bethak Road, Khambhat, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7406.94132

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The purpose of this research was to design, and evaluate multiparticulate systems for Chronotherapeutic delivery of beta blocker containing biodegradable polymers coated with pH sensitive polymers in hypertension. Chitosan was used as a carrier for drug delivery and Eudragit S100 was used as an enteric coating polymer. 3 2 full factorial design was employed to optimize the proper formulation for Chronotherapeutic drug delivery.


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