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REVIEW ARTICLE
Year : 2013  |  Volume : 5  |  Issue : 4  |  Page : 253-256

Effects of moxonidine on sympathetic nervous system activity: An update on metabolism, cardio, and other target-organ protection


1 Department of Internal Medicine, AHEPA Hospital, Thessaloniki, Greece
2 Department of Internal Medicine-Propaedeutic, Gastroenterology Division, Laikon General Hospital, University of Athens, Athens, Greece
3 Department of Biochemistry, Medical School, Aristotles University of Thessaloniki, Thessaloniki, Greece

Correspondence Address:
Christos G Savopoulos
Department of Internal Medicine, AHEPA Hospital, Thessaloniki
Greece
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7406.120067

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Moxonidine is the newest, second-generation, centrally acting antihypertensive agent. It has selective agonist activity at imidazoline I1 receptors and less adverse effects than the other centrally acting drugs. This fact authorizes the frequent use of moxonidine in clinical practice, as monotherapy or in combination with other antihypertensive agents. Also, moxonidine has beneficial effects in obese and metabolic syndrome and in target-organs, such as heart and kidneys.


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