|DENTAL SCIENCE - CASE REPORT
|Year : 2014 | Volume
| Issue : 5 | Page : 196-199
Adenomatoid odontogenic tumor in the maxillary antrum: A rare case entity
Kavitha Krishnamurthy1, Ranjith Singh Balaji1, Sumana Devadiga2, Rame Gowda Rajendra Prasad3
1 Department of Dentistry, Adichunchanagiri Institute of Medical Sciences, B.G. Nagara, Karnataka, India
2 Consulting Maxillo-Facial Surgeon, Mangalore, Karnataka, India
3 Department of Oral and Maxillo Facial Surgery, JSS Dental College, JSS University, Mysore, KarnatakaDepartment of Oral and Maxillo Facial Surgery, JSS Dental College, JSS University, Mysore, Karnataka, India
|Date of Submission||18-Apr-2014|
|Date of Decision||18-Apr-2014|
|Date of Acceptance||23-Apr-2014|
|Date of Web Publication||25-Jul-2014|
Dr. Kavitha Krishnamurthy
Department of Dentistry, Adichunchanagiri Institute of Medical Sciences, B.G. Nagara, Karnataka
Source of Support: None, Conflict of Interest: None
| Abstract|| |
Adenomatoid odontogenic tumor (AOT) is an uncommon benign tumor of odontogenic origin. It occurs in the second decade of life. Females are more commonly affected than males. AOT has a striking tendency to occur in the anterior maxilla; however, very few cases have been reported to occur in the maxillary antrum. This is a case report of a 17-year-old male presented with a large radiolucent lesion associated with the crown of an unerupted canine located in the right maxillary antrum, which was clinically diagnosed as dentigerous cyst. The histopathological examination revealed the presence of AOT.
Keywords: Adenomatoid odontogenic tumor, impacted tooth, maxillary antrum
|How to cite this article:|
Krishnamurthy K, Balaji RS, Devadiga S, Prasad RR. Adenomatoid odontogenic tumor in the maxillary antrum: A rare case entity. J Pharm Bioall Sci 2014;6, Suppl S1:196-9
|How to cite this URL:|
Krishnamurthy K, Balaji RS, Devadiga S, Prasad RR. Adenomatoid odontogenic tumor in the maxillary antrum: A rare case entity. J Pharm Bioall Sci [serial online] 2014 [cited 2020 May 26];6, Suppl S1:196-9. Available from: http://www.jpbsonline.org/text.asp?2014/6/5/196/137468
Adenomatoid odontogenic tumor (AOT), an uncommon benign epithelial lesion of odontogenic origin was first described by Dreibaldt in 1907 as a pseudo-adenoameloblastoma.  It was only in 1948 when, Stafne considered it as distinct pathological entity.  The current WHO classification of odontogenic tumors defines AOT as being composed of odontogenic epithelium in a variety of histoarchitectural patterns, embedded in a mature connective tissue stroma and characterized by slow, but progressive growth.  The differential diagnosis of AOT is crucial in terms of surgical management. Local excision is adequate to free the patient from AOT. 
This is a rare case report of an AOT in the maxillary antrum in association with an impacted canine, which mimicked dentigerous cyst clinically and radiographically.
| Case Report|| |
A 17-year-old male presented with the chief complaint of swelling on the right side of the face since 6 months. He gave a history of gradual increase in size of the swelling.
On extra oral examination, swelling measured approximately 4 cm × 3 cm, hard on palpation, with a smooth surface extending from ala of the nose to about 2 cm in front of the tragus of the ear and about 1 cm below the infraorbital rim to ala tragal line with the obliteration of the nasolabial fold on the right side.
On intra oral examination, swelling measured approximately 3 cm × 2 cm, firm on palpation, with a smooth surface extending from left central incisor to right first molar [Figure 1]. The right upper canine, right and left lateral incisors were missing. Over retained deciduous right central incisor, right lateral incisor, right canine, and left canine were noted. Grade III mobility of all the over retained deciduous teeth and right first premolar was noted. There was no evidence of oro-nasal and oro-antral communication, and the palatal mucosa was intact.
Water's view projection revealed haziness with respect to bilateral maxillary antrum.
Computed tomography (CT) scan demonstrated expansile lytic lesion extending into the nasal cavity and right maxillary antrum with obliteration of the respective lumen in association with an impacted tooth [Figure 2].
Fine-needle aspiration was done, which yielded about 15 ml of straw-colored fluid.
Based on the clinical and radiographic findings, the differential diagnosis of dentigerous cyst, unicystic ameloblastoma and AOT was made.
The patient was operated by raising the mucoperiosteal flap intraorally. The lining of the cystic lesion was carefully separated from the mucoperiosteum and the lesion was enucleated. The impacted canine, first premolar, and all retained deciduous teeth were extracted [Figure 3]. The specimen was then submitted for histopathological examination [Figure 4].
Histopathological sections showed a cystic wall lined by epithelial cells in sheets, clusters, nests and islands and also cells in ductal, cribriform and trabecular pattern, ducts lined by columnar epithelium resembling ameloblasts, areas of rosette formation, eosinophilic hyaline material deposition and dystrophic calcifications, giving the impression of AOT [Figure 5].
Healing was uneventful [Figure 6].
| Discussion|| |
Adenomatoid odontogenic tumor was first recognized as a distinct pathological entity by Stafne in 1948. AOT is a slow growing benign tumor, constituting only 3% of all odontogenic tumors  and 0.1% of tumors of jaws. The lesion is usually asymptomatic. The adjacent teeth may be slightly displaced. 
Most common site of AOT is anterior region of maxilla. Tajima et al.  described an AOT located in the superior portion of the maxillary sinus. Based on the location, three variants of AOT, the follicular type (73%), the extra follicular type (24%), and the peripheral type (3%) has been described. ,
The female to male ratio for all age groups and all variants is close to 2:1.  The tooth that is impacted commonly is the canine in 40%. 
Conservative surgical enucleation is the treatment modality of choice. Recurrence of AOT is exceptionally rare. Therefore, the prognosis is excellent.  With respect to the age of the patient and the localization of the AOT in the maxillary antrum, which was extending from midline to molar region (as shown in CT) the reported case is a rare example of this tumor entity. Due to its low tendency to recur, the case here by presented was treated by conservative surgical enucleation associated with the removal of the unerupted dental element and such procedure was proposed in numerous papers.
| Conclusion|| |
Clinical, radiographic, and microscopic findings in this case are consistent with descriptions of the lesion in the dental literature. As previously mentioned AOT is usually solid, but is occasionally cystic. The structure of the cyst and its insertion around the crown of an unerupted tooth were typical of a dentigerous cyst. However, in this case, the multifocal cellular proliferation had the structure of an AOT [Figure 7] and [Figure 8].
Conservative surgical enucleation or curettage is the treatment of choice for AOT. Prognosis is good. Recurrences are rare.
Very few histologically diagnosed case reports of AOT in the maxillary antrum have previously been reported. In this case, the final diagnosis of an AOT was arrived by histopathological examination of the enucleated tissue specimen. Rarity of the case is in the fact that the AOT involved the maxillary antrum, was extensive and the treatment resulted in good prognosis.
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[Figure 1], [Figure 2], [Figure 3], [Figure 4], [Figure 5], [Figure 6], [Figure 7], [Figure 8]