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 Table of Contents  
ORIGINAL ARTICLE
Year : 2018  |  Volume : 10  |  Issue : 3  |  Page : 159-165  

Ethnopharmacological uses and public knowledge regarding Cinnamomum zeylanicum in Khobar, Saudi Arabia


1 College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
2 Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
3 Department of Pharmacy Practice, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia
4 Department of Pharmaceutics, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia

Date of Web Publication30-Aug-2018

Correspondence Address:
Dr. Rizwan Ahmad
Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam
Kingdom of Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JPBS.JPBS_71_18

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   Abstract 


Background: Cinnamon (Cinnamomum zeylanicum) is a herb that is used traditionally as a flavoring agent as well as for its health benefits in different parts of the world. Its use may vary among cultures. Aim: To observe the knowledge and uses regarding cinnamon in the Saudi population. Materials and Methods: A 2-month cross-sectional study was conducted in Khobar, Saudi Arabia, using a novel questionnaire in Arabic language. Results: A total of 585 responses were collected. Most respondents were female (91.5%), adults (74.4%), married (65.6%), and had bachelor’s degree (58.1%). A total of 84.3% knew about cinnamon and used cinnamon as bark (38.6%) and as a flavoring agent (74.7%). Most common reason for use was to ease menstruation and menstrual pain (49.9%), as antidiabetic (35.9%), and for weight loss (5.6%). The source of information for cinnamon use and its knowledge was family and relatives who were using cinnamon (75.9%), that is, folkloric use. Conclusion: Folkloric use of cinnamon was found to influence the knowledge and usage of cinnamon in the Saudi population.

Keywords: Antidiabetic, Arab community, cinnamon, folklore uses, gynecological problems


How to cite this article:
Almubayedh H, Ahmad R, Naqvi AA, Ahmad N. Ethnopharmacological uses and public knowledge regarding Cinnamomum zeylanicum in Khobar, Saudi Arabia. J Pharm Bioall Sci 2018;10:159-65

How to cite this URL:
Almubayedh H, Ahmad R, Naqvi AA, Ahmad N. Ethnopharmacological uses and public knowledge regarding Cinnamomum zeylanicum in Khobar, Saudi Arabia. J Pharm Bioall Sci [serial online] 2018 [cited 2018 Dec 13];10:159-65. Available from: http://www.jpbsonline.org/text.asp?2018/10/3/159/240121




   Introduction Top


Plants were the first medicines known by humans. People believed in the healing powers of plants and have been using them as early as 60,000 years ago.[1],[2] The plants containing active phytochemicals were used to treat different diseases and alleviate pain.[3] Due to the increasing use of herbs for therapeutic purposes, herbalism (the study of herbs) emerged and built the foundation of botany, modern medicine, and pharmacy.[4] In the early nineteenth century, the isolation of medicinal active phytochemicals began and marked the beginning of scientific pharmacy.[3]

Herbs and medicinal plants were an area of interest for the ancient Arab physicians and scientists. Ibn-Hayan along with other Arab chemists extracted general and local anesthetics from Cannabis sativa, Hyoscyamus aureus, and Papaver somniferum. Approximately 350 species of medicinal plants were discovered by Ibn-AlBitar and other Arab botanists, physicians, and pharmacologists. Arabs have contributed a lot in the early development of herbal medicine. However, the number of scientifically well-oriented and experienced herbalists is few. Currently in Arab traditional medicine, less than 250 species of plants are still used for therapeutic purposes. This is due to the detrimental climatic and environmental changes as well as the ongoing destruction of their natural habitat in the Middle East. Nevertheless, local medicinal herbs are still in use for the treatment of different diseases. Plants such as Anchusa strigosa, Alchemilla vulgaris, and Calotropis procera were used in Arabic medicine for skin diseases. For the treatment of cancer, Arum palaestinum, Allium cepa, and Brassica oleracea were used.[5] Traditional use of plants by the Arabs was reported in the literature for Bedouins of Sinai and the Negev. For the treatment of cough, Bedouins used the leaves of Artemisia herba-alba and Haplophyllum tuberculatum with milk as a drink. Cassia italica’s leaves tea and the roots of Convolvulus hystrix and Euphorbia hierosolymitana have been used for treating constipation. Leaves of Achillea fragrantissima, Varthemia iphionoides, and Haplophyllum tuberculatum were used to bath patients having fever.[6] In traditional Yemeni medicine, it is believed that coffee enhances the effects of honey, moreover, honey and plain coffee have been used to treat anemia. In addition, coffee husk decoction flavored with cardamom and ginger is believed to have the best healing properties.[7] In Bahrain, boiled roots or fruits of Citrullus colocynthis (murrah) are used for the treatment of jaundice and are also used as a cathartic, hydragogue, and diuretic. Plantago coronopus L. is also used traditionally in Bahrain as a laxative.[8]

A rich tradition is found in Saudi Arabia regarding the use of medicinal plants. Trigonella foenum-graecum L., locally known as hulba, is widely used among Saudi women for menstrual disorders. Hulba is also used as an aphrodisiac and in diabetes to control blood glucose level. Elettaria cardamomum Maton (heil) is widely used in Arabic coffee and traditional foods such as kapssa as a spice. It is also known for its health benefits as a stimulant and carminative. Curcuma longa L. (curcum) is used as a paste applied on contusions and sprain. Fruits of Piper longum L. (filfil) are used in the treatment for cold, cough, and headache. Lawsonia inermis L. (henna) leaves are widely used as a coloring agent for skin and hair. It is believed that henna reduces body heat and treats skin and liver problems. The most common traditional drink in Saudi Arabia is the decoction of Coffea arabica (qahwa). It is known for its stimulant and diuretic activity. Wood from Aquilaria agallocha (oud) is widely used in Saudi Arabia and is known as a carminative and an aphrodisiac.[9]

Cinnamomum zeylanicum (cinnamon), locally known as kurfah, is derived from Lauraceae family. The tropical tree of C. zeylanicum grows wild in India, Sri Lanka, Indochina, and Madagascar.[10]C. zeylanicum contains diverse phytochemicals that were isolated and identified from its crude extract. Few of which include (E)-cinnamaldehyde,[11]trans-cinnamic acid, trans-cinnamyl acetate, cinnzeylanine, cinnzeylanol, and cinnamtannin B-1.[12] In a number of cultural groups around the world, cinnamon barks have been used as a flavoring agent/spice in different types of food. Traditionally and until today, cinnamon is used for gastrointestinal complaints as a stomachic and carminative agent. In aromatherapy, cinnamon oil is used to enhance the mood. As a diagnostic tool, cinnamon is used in selective olfactory defect test in individuals with Parkinson’s disease to diagnose Parkinson’s disease–related hyposmia. The ethanolic extract from cinnamon has been proven, by hot plate–induced thermal stimulation and acetic acid–induced writhing in mice, to have antinociceptive (analgesic) effects. Cinnamon, alone or as a combination with oregano and fenugreek, has proven to control blood glucose level in humans and animals.[13] The study conducted on 60 Arabic patients having diabetes mellitus (DM) type 1 revealed a decrease in lipid and glucose levels.[14]

Cinnamon is used widely in the Middle East. It is often added to savory dishes in the Middle Eastern cuisine.[13] Reported uses of cinnamon by the Middle Eastern women during pregnancy were for stomach aches and bloating.[15] In a survey of 166 patients with diabetes using herbs in Jordan, 3.6% of the patients used cinnamon to control their glucose level.[16] According to an ethnopharmacological survey conducted in Jordan, cinnamon was known to clean female genital system.[17] In Saudi Arabia (Makkah Al-Mukarramah), an ethnobotanical research survey was conducted. According to this survey, the folkloric use in the Western Province of Saudi Arabia for cinnamon was as carminative, antiseptic, and for checking nausea and vomiting.[9] As no ethnobotanical and ethnopharmacological study was conducted to study the knowledge and use of cinnamon in the Eastern Province of Saudi Arabia, this article will evaluate the knowledge and use of cinnamon in this region.


   Materials and Methods Top


A quantitative cross-sectional study was conducted in the common population living in the Eastern Province of Saudi Arabia.

Duration and venue of the study

The duration of the study was 2 months, that is, January and February 2018, and it was conducted in the city of Khobar, Saudi Arabia.

Target population and exclusion criteria

The target population was the public residing in Khobar City, Eastern Province of Saudi Arabia. Both male and female citizens irrespective of education as well as participants above 12 years were included in the study. Non-consenting participants were not included.

Research instrument and translation

The questionnaire used in the study was developed in English language and was translated in Arabic before handing to the respondents. The translation was carried as per the standard guidelines.[18] The initial draft was prepared by an Arabic speaker whose second language was English, and it was back translated by another colleague with the same language competence. The English version was validated by two academic professors.

Validation of questionnaire

The tool was content validated in two rounds of meetings by a panel of experts including two clinical pharmacists, herbalist, and two academic professors. All questions were content validated and had minimum content validity ratio above 0.81. The content validity index was 0.87.

A total of 10 questions were included in the research instrument. The questionnaire consisted of five (05) sections that are demographic information; knowledge regarding cinnamon; prevalence of cinnamon use; part used, reasons for use, and health benefits of cinnamon; and source of information regarding cinnamon. The reliability analysis reported a Cronbach’s alpha value of 0.62.

Sampling procedure and sample size

An online survey was conducted. Population-based sample size calculation was carried out and a convenient sampling method was selected. Official figure for the population of Eastern Province was reported to be 3,144,578 individuals.[2] This figure was used to calculate the sample size using online sample size calculator. The required sample size was reported as 385.[19]

Data analysis

Data were entered in IBM Statistical Package for the Social Sciences (SPSS) Statistics for Windows, Version 22.0 (IBM, Armonk, NY). Data were expressed in sample count (N) and percentage (%). Chi-square (χ2) test was used to report any association between demographics and uses as well as knowledge regarding cinnamon. Statistical significance was considered at P < 0.05.

Consent of the participants and ethics approval

All the participants were briefed about the study and a written informed consent was obtained from them. Subjected to participant willingness, the online questionnaire was filled and their response was recorded. This study was approved by the Department of Natural Products and Alternative Medicine, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Kingdom of Saudi Arabia with approval number Ref. no. 2160002152.


   Results Top


Demographic characteristics of respondents

A total of 585 responses were collected and majority of the participants comprised adults (n = 435/585, 74.4%). Most of the participants were female (n = 535/585, 91.5%) and were married (n = 384/585, 65.6%). Almost half of them had a bachelor’s degree (n = 340/585, 58.1%). The summary for demographics characteristics is shown in [Table 1].
Table 1: Demographic characteristics of the respondents

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Knowledge of the respondents regarding uses of cinnamon (know/purpose/form)

Majority of the respondents knew about cinnamon (n = 493/585, 84.3%). Most of them used cinnamon as a flavoring agent (n = 437/585, 74.7%). Almost one-third of them used cinnamon bark (n = 226/585, 38.6%). The summary for the knowledge about cinnamon use is given in [Table 2].
Table 2: Knowledge about cinnamon use

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Medical and general health benefits of cinnamon

One-third of the respondents used cinnamon once a month (n = 199/585, 34%). Approximately half of the respondents believed cinnamon to ease menstruation and menstrual pain (n = 292/585, 49.9%), followed by the respondents who believed it to regulate blood glucose level and mimic insulin’s effect (n = 210/585, 35.9%). Furthermore, weight loss activity (n = 33/585, 5.6%), miscellaneous uses (regulates hormones and metabolic activity, increases hemoglobin levels, contains minerals, treats cold, acts as diuretic agent, and reduces cholesterol) (n = 25/585, 4.3%), digestive activity (n = 16/585, 2.7%), and anticoagulant activity (n = 9/585, 1.5%) were also reported by the respondents. Majority of the respondents knew about the benefits of cinnamon from their family members and relatives, that is, folkloric use (n = 444/585, 75.9%). The summary for health benefits/medical uses for cinnamon is given in [Table 3].
Table 3: Health benefits/medical uses for cinnamon

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Prevalence of cinnamon use

The prevalence of cinnamon use was reported at 45.47% for 2 months. The individual prevalence for different demographics are tabulated in [Table 4].
Table 4: Prevalence of cinnamon

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Association of demographics with knowledge

The demographics of the respondents such as age, gender, educational level, and marital status were cross tabulated with knowledge variables. The age was weakly associated with the knowledge of cinnamon (χ2 = 1.70, P < 0.42, phi = 0.05). Similarly, age was associated with the parts used (χ2 = 13.54, P < 0.05, phi = 0.15). Marital status and education were significantly associated with the same (χ2 = 64.7, P < 0.001, phi = 0.3 and χ2 = 22.4, P < 0.05, phi = 0.19, respectively). The summary of cross tabulation is reported in [Table 5].
Table 5: Cross tabulation of demographics versus knowledge about cinnamon

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   Discussion Top


Cinnamon as a spice is used since long in diverse cultures for various purposes. In addition to its culinary uses, cinnamon is known for its uses as antioxidant, antidiabetic, digestive aid, antibacterial as well as in respiratory disorders and gynecological ailments. The bark of cinnamon is used mostly for health and other purposes; however, the essential oil obtained from the bark may also be used for various purposes. On the basis of folkloric uses, cinnamon has distinguished uses among distinct population. An attempt was made to report ethnobotanical and ethnopharmacological uses and knowledge regarding cinnamon in cities located in the Eastern Province of Saudi Arabia.

An overwhelming proportion of the respondents knew about cinnamon, and mostly they used it as a flavoring agent in their foods. Cinnamon is well known for its flavoring and aromatic properties and is used in various foods, bakeries, sweets, and drinks as a flavoring agent.[13],[20] Cinnamon is also used as a flavoring agent in pharmaceutical preparations such as toothpastes, mouth fresheners, and mouthwashes. Cinnamon is used in the Western cuisine with other natural products such as clove, anise, and nutmeg in baked gingerbread.[13],[21] Our findings were in line with the previous reports regarding use of cinnamon as a flavoring agent.

Though cinnamon is available as bark, powder, and essential oil, most respondents in our study used the bark. This may be due to availability and low price of the bark as compared to oil or powder. In addition, the storage requirements for cinnamon bark are relatively less rigid as compared to other forms. The bark can be stored at room temperature and used for up to 2 years, whereas powder has a shorter shelf life.[22] Moreover, cinnamon essential oil is a concentrated product, which is mostly used for therapeutic purposes.[23],[24] Thus, the bark is more convenient to use for consumers.

The most common use of cinnamon as reported by the public was for the ease of menstruation and menstrual pain. Numerous studies have reported cinnamon as an aid for the ease of menstruation and in reducing the intensity of pain associated with menstrual cycle.[25],[26] Hence, our findings are in congruence with reported literature.[27] The second most common use reported was in the regulation of blood sugar level. Cinnamon possesses antidiabetic property; this effect is exerted through polyphenols, which improve insulin sensitivity.[14],[16],[28]

Traditionally, cinnamon has been used for treating DM in China.[29] In addition, folkloric use and knowledge of cinnamon have been reported in some studies.[27],[30] Our study supports the use of cinnamon as an antidiabetic as reported by Ahmad et al.[27] in the same population. A small fraction used it as a digestive aid and for weight loss. Cinnamon has been reported to increase the bile flow along with the total amount of biliary solid matters. Studies have reported the use of cinnamon in Jordanian pregnant women as a digestive and carminative agent. Hence, our finding supports the same.[31] Regarding weight loss, cinnamon has been reported to reduce serum level of the total cholesterol, low-density lipoprotein, and triglycerides, and to increase high-density lipoprotein.[32],[33] As mentioned by Klop et al.,[34] one of the metabolic risks of obesity is hyperlipidemia. Cinnamon may be helpful in weight loss because of its antihyperlipidemic activity; however, no study has reported cinnamon’s weight loss activity. This is a novel finding, that is, folkloric use in the Arab community.

The uses of cinnamon in our study were found to be attributed to the use by family or relatives and the knowledge from them. Three quarters of respondents used cinnamon based on its use in family. Hence, it was evident that the folkloric use of plants was a determinant use and knowledge regarding cinnamon. The folkloric use refers to the use of herbs in ancient times and its subsequent transfer through generations.[35]

This study provides valuable information regarding the use of cinnamon in the Arab community. Two major strengths were observed in this study. We developed a novel questionnaire that was content validated and subsequently translated in Arabic language. Another strength of this study was to document data from many respondents that exceeded the required sample size. The study employed convenient sampling that limits its generalizability across the Saudi population. Further studies are recommended in patients with diabetes and hyperlipidemia to investigate general knowledge about the herb as well as its use as it affects blood glucose level.


   Conclusion Top


Folkloric use of cinnamon was found to influence knowledge and usage of cinnamon in the Saudi population.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
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    Tables

  [Table 1], [Table 2], [Table 3], [Table 4], [Table 5]



 

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