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ORIGINAL ARTICLE
Year : 2020  |  Volume : 12  |  Issue : 5  |  Page : 352-354

Evaluation of antimicrobial efficacy of calcium hydroxide along with proton pump inhibitor against Enterococcus faecalis


1 Department of Conservative Dentistry and Endodontics, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India
2 Department of Oral Pathology and Microbiology, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India

Correspondence Address:
Namitha Divakar
Department of Conservative Dentistry and Endodontics, Sree Anjaneya Institute of Dental Sciences, Nandanam, Kunnummel, Paroppady Kannadikkal Road, Vengeri (PO), Calicut, Kerala.
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpbs.JPBS_104_20

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Aim: The aim of this study was to evaluate in vitro the efficacy of pantoprazole, a proton pump inhibitor, alone, and in combination with calcium hydroxide against Enterococcus faecalis, a star survivor in endodontic pathology. Materials and Methods: Teeth were inoculated with E. faecalis strains MTCC 439 and were divided into groups. Group 1 used saline as the negative control, Group 2 used calcium hydroxide, Group 3 used pantoprazole alone, and Group 4 used calcium hydroxide along with pantoprazole. They were incubated and dentine harvesting was performed. Colonies were counted using a digital counting machine. Data were statistically analyzed. Results: Group 4 was found to be the most effective against the pathogen. Discussion: This study indicates that the association of calcium hydroxide with the proton pump inhibitor pantoprazole can be successfully used as an intracanal medicament against E. faecalis.


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