Journal of Pharmacy And Bioallied Sciences

PROLOGUE
Year
: 2012  |  Volume : 4  |  Issue : 5  |  Page : 0-

Prologue


Naazneen Surti 
 Chief Coordinator for the National Conference

Correspondence Address:
Naazneen Surti
Chief Coordinator for the National Conference




How to cite this article:
Surti N. Prologue.J Pharm Bioall Sci 2012;4:0-0


How to cite this URL:
Surti N. Prologue. J Pharm Bioall Sci [serial online] 2012 [cited 2020 Sep 22 ];4:0-0
Available from: http://www.jpbsonline.org/text.asp?2012/4/5/0/94235


Full Text

Efficacy of a drug is significantly affected by the method by which it is delivered. Drug delivery could be defined broadly as physical dosage form, molecular design or other physical approaches built on the fundamentals of metabolism, pharmacokinetic-pharmacodynamic interactions. Drug delivery systems are based on interdisciplinary approaches that combine polymer science, pharmaceutics, bioconjugate chemistry, and molecular biology. To minimize drug degradation and loss, to minimize side effects and to increase drug bioavailability and fraction of drug getting accumulated at the target site, various drug delivery technologies are under development.

An FDA survey found that only 9% of the 99 new small molecule drugs introduced in the last decade were Class I high solubility and permeability, which facilitates conventional oral delivery. Thus the expanding arena of emerging drugs combined with increased sensitivity to clinical outcomes and healthcare costs are driving the need for alternative drug delivery methods and devices. More and more, the development of drugs and the development of delivery systems are being integrated to optimize the efficacy and cost effectiveness of the therapy.

The drug delivery technologies showing promising results include polymeric carriers like micro and nanoparticles, micelles, liposomes, dendrimers, nanocrystal technology, ligand conjugated delivery, hydrogels etc. to name a few. However only a limited number of these platforms or technologies have advanced to clinical evaluation. Therefore, a systematic review of drug delivery technologies currently in development could provide an important insight on the progress and the emerging trend in translation of drug delivery concepts into pharmaceutical products. Hence this conference on Advances in Drug Delivery Technologies was planned to get researchers from all over India updated on the opportunities and challenges of this area.

Several research papers were received for presentation at the conference, out of which 50 were selected for publication in this volume. This volume includes research papers describing novel technologies to optimize drug delivery like methods for intracellular delivery of genetic material, methods based on nanotechnology for increasing the solubility of poorly soluble drugs, stimuli sensitive systems, nanocrystal technology, chronotherapeutics based delivery of antihypersensitive drug, and controlled and site specific drug delivery. The abstract of the talks to be delivered by the expert speakers at the conference have also been included in this volume. I am sure that these write-ups would prove to be informative and useful.