Journal of Pharmacy And Bioallied Sciences

REVIEW ARTICLE
Year
: 2018  |  Volume : 10  |  Issue : 4  |  Page : 173--180

Saffron (Crocus sativus L.): As an antidepressant


Mohammad J Siddiqui, Mohammed S M Saleh, Siti N B Binti Basharuddin, Siti H Binti Zamri, Mohd H bin Mohd Najib, Muhammad Z Che Ibrahim, Nur A binti Mohd Noor, Hanin N Binti Mazha, Norazian Mohd Hassan, Alfi Khatib 
 Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia

Correspondence Address:
Dr. Mohammad J Siddiqui
Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Indera Mahkota, Jalan Istana, Kuantan 25200, Pahang
Malaysia

Saffron, Crocus sativus (Iridaceae), is a perennial herb, which earned its popularity as both medicine and spice. It is an inhabitant of different mountainous regions of Asia Minor to Greece, Western Asia, Egypt, and India. The benefits of saffron as an antidepressant are well-documented. Almost 150 volatile and nonvolatile compounds are obtained from the chemical analysis of this plant. Fewer than 50 constituents elucidated and identified so far showed phytochemical characteristics. The major bioactive compounds identified are safranal, crocin, and picrocrocin, which are responsible for its aroma as well as its bitter taste. This review is an attempt to encompass the methods of analysis and pharmacodynamic and pharmacokinetic properties of saffron followed by its efficacious and safe potential.


How to cite this article:
Siddiqui MJ, Saleh MS, Basharuddin SN, Zamri SH, Mohd Najib MH, Che Ibrahim MZ, binti Mohd Noor NA, Binti Mazha HN, Mohd Hassan N, Khatib A. Saffron (Crocus sativus L.): As an antidepressant.J Pharm Bioall Sci 2018;10:173-180


How to cite this URL:
Siddiqui MJ, Saleh MS, Basharuddin SN, Zamri SH, Mohd Najib MH, Che Ibrahim MZ, binti Mohd Noor NA, Binti Mazha HN, Mohd Hassan N, Khatib A. Saffron (Crocus sativus L.): As an antidepressant. J Pharm Bioall Sci [serial online] 2018 [cited 2019 Jan 22 ];10:173-180
Available from: http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2018;volume=10;issue=4;spage=173;epage=180;aulast=Siddiqui;type=0