Journal of Pharmacy And Bioallied Sciences

REVIEW ARTICLE
Year
: 2020  |  Volume : 12  |  Issue : 5  |  Page : 20--26

Regenerative endodontics: A paradigm shift in clinical endodontics


Manoj Kumar Pulyodan1, Sunil Paramel Mohan2, Dhanya Valsan1, Namitha Divakar1, Shabna Moyin1, Shamsheer Thayyil1 
1 Department of Conservative Dentistry and Endodontics, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India
2 Department of Oral Pathology and Microbiology, Sree Anjaneya Institute of Dental Sciences, Calicut, Kerala, India

Correspondence Address:
Dhanya Valsan
Department of Conservative Dentistry and Endodontics, Sree Anjaneya Institute of Dental Sciences, Calicut 673315, Kerala
India

Preserving the natural dentition in its normal form and function is one of the major goals of endodontic treatment. Re-establishing the lost vitality and development of root maturation in immature permanent teeth with pulp necrosis/apical periodontitis is quiet challenging clinically. The very basis of regenerative endodontics relies on the concept of tissue engineering using stem cells, biomimetic scaffold, and bioactive growth factors to regenerate the pulp tissue damaged by microbial infection, injury, or developmental defects. In clinical endodontics, this approach is referred to as a “paradigm shift.” Even though repair instead of true regeneration is achieved with current protocols, it is hoped that further research in the area of stem-cell-based tissue engineering will allow for true regeneration and improved treatment outcomes. The aim of this review is to discuss about the various aspects of regenerative endodontics, current clinical protocols, and the future of pulp regeneration techniques.


How to cite this article:
Pulyodan MK, Mohan SP, Valsan D, Divakar N, Moyin S, Thayyil S. Regenerative endodontics: A paradigm shift in clinical endodontics.J Pharm Bioall Sci 2020;12:20-26


How to cite this URL:
Pulyodan MK, Mohan SP, Valsan D, Divakar N, Moyin S, Thayyil S. Regenerative endodontics: A paradigm shift in clinical endodontics. J Pharm Bioall Sci [serial online] 2020 [cited 2020 Sep 18 ];12:20-26
Available from: http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2020;volume=12;issue=5;spage=20;epage=26;aulast=Pulyodan;type=0