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  Indian J Med Microbiol
 

Figure 1: Schematic representation of the gene therapy approach mediated respectively by: (a) Gene transfer into hematopoietic stem cells (HSCs) using integration-competent lentiviral vector. (b) Gene transfer into hematopoietic stem cells (HSC) integrase defective lentiviral vectors. ZFN: Zinc figure protein. (c): Stem cell therapy reprogramming of adult cells to stem cells. iPS: Induced pluripotent stem cells

Figure 1: Schematic representation of the gene therapy approach mediated respectively by: (a) Gene transfer into hematopoietic stem cells (HSCs) using integration-competent lentiviral vector. (b) Gene transfer into hematopoietic stem cells (HSC) integrase defective lentiviral vectors. ZFN: Zinc figure protein. (c): Stem cell therapy reprogramming of adult cells to stem cells. iPS: Induced pluripotent stem cells