Close
  Indian J Med Microbiol
 

Figure 3: Effect of exogenous supplementation of l-cysteine (Cys) along with adsorbed ascites fluid (ad-AF) treatment on the alterations in the activities of phase-I and phase-II biotransformation enzymes in the liver of tumor bearer and treated mice. Animals in each group were transplanted with 1×106 Ehrlich’s ascites tumor cells intraperitoneally (i.p.); Group-I (tumor control) was administered 0.1mL of normal saline, Group-II (tumor experimental) received 0.1mL of ad-AF, whereas Group-III (tumor experimental + Cys) was treated with 0.1mL of ad-AF and Cys (0.1mL) i.p. on alternate days right from the day of tumor transplantation (day 0). Animals were killed by cervical dislocation on day 18 post-tumor transplantation. Activities of biotransformation enzymes were measured in liver. First group of bars represent the activity of aminopyrine-N-demethylase (AD), second group of bars represent the activity of aniline hydroxylase (AH), whereas the third group of bars represent the activity of glutathione S-transferase (GST). Values are mean ± standard error (SE) of five animals in each group. *P < 0.05, **P < 0.005

Figure 3: Effect of exogenous supplementation of <sc>l</sc>-cysteine (Cys) along with adsorbed ascites fluid (ad-AF) treatment on the alterations in the activities of phase-I and phase-II biotransformation enzymes in the liver of tumor bearer and treated mice. Animals in each group were transplanted with 1×10<sup>6</sup> Ehrlich’s ascites tumor cells intraperitoneally (<i>i.p.</i>); Group-I (tumor control) was administered 0.1mL of normal saline, Group-II (tumor experimental) received 0.1mL of ad-AF, whereas Group-III (tumor experimental + Cys) was treated with 0.1mL of ad-AF and Cys (0.1mL) <i>i.p.</i> on alternate days right from the day of tumor transplantation (day 0). Animals were killed by cervical dislocation on day 18 post-tumor transplantation. Activities of biotransformation enzymes were measured in liver. First group of bars represent the activity of aminopyrine-<i>N</i>-demethylase (AD), second group of bars represent the activity of aniline hydroxylase (AH), whereas the third group of bars represent the activity of glutathione <i>S</i>-transferase (GST). Values are mean ± standard error (SE) of five animals in each group. *<i>P</i> < 0.05, **<i>P</i> < 0.005