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DENTAL SCIENCE - REVIEW ARTICLE
Year : 2012  |  Volume : 4  |  Issue : 6  |  Page : 307-309

Applications of immunohistochemistry


1 Department of Oral and Maxillofacial Pathology, Thai Moogambigai Dental College & Hospital, Chennai, India
2 Department of Oral and Maxillofacial Pathology, J K K Nataraja Dental College & Hospital, Komarapalayam, Namakkal, Tamil Nadu, India
3 Department of Bio Chemistry, J K K Nataraja Dental College & Hospital, Komarapalayam, Namakkal, Tamil Nadu, India

Correspondence Address:
Karunakaran Kaliyappan
Department of Oral and Maxillofacial Pathology, J K K Nataraja Dental College & Hospital, Komarapalayam, Namakkal, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7406.100281

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Immunohistochemistry (IHC) is an important application of monoclonal as well as polyclonal antibodies to determine the tissue distribution of an antigen of interest in health and disease. IHC is widely used for diagnosis of cancers; specific tumor antigens are expressed de novo or up-regulated in certain cancers. This article deals with the various applications of IHC in diagnosis of diseases, with IHC playing an important role in diagnostic and research laboratories.


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