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DENTAL SCIENCE - REVIEW ARTICLE
Year : 2015  |  Volume : 7  |  Issue : 5  |  Page : 209-212

Immunologically mediated oral diseases


1 Department of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamil Nadu, India
2 Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Sudha Jimson
Department of Oral Pathology, Sree Balaji Dental College and Hospital, Bharath University, Chennai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0975-7406.155909

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Immune mediated diseases of oral cavity are uncommon. The lesions may be self-limiting and undergo remission spontaneously. Among the immune mediated oral lesions the most important are lichen planus, pemphigus, erythema multiformi, epidermolysis bullosa, systemic lupus erythematosis. Cellular and humoral mediated immunity play a major role directed against epithelial and connective tissue in chronic and recurrent patterns. Confirmatory diagnosis can be made by biopsy, direct and indirect immunoflouresence, immune precipitation and immunoblotting. Therapeutic agents should be selected after thorough evaluation of immune status through a variety of tests and after determining any aggravating or provoking factors. Early and appropriate diagnosis is important for proper treatment planning contributing to better prognosis and better quality of life of patient.


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