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Year : 2017  |  Volume : 9  |  Issue : 5  |  Page : 191-196

Comparative evaluation of serum lipid profile in patients with oral submucous fibrosis and oral squamous cell carcinoma with that of control subjects: A case control study

1 Department of Oral Medicine and Radiology, Vinayaka Missions Sankarachariyar Dental College, Salem, Tamil Nadu, India
2 Department of Conservative Dentistry and Endodontics, Vinayaka Missions Sankarachariyar Dental College, Salem, Tamil Nadu, India

Correspondence Address:
A Cicilia Subbulakshmi
6/3, Chaithanya Appartments, 5th Cross, Brindhavan Road, Fairlands, Salem - 636 016, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpbs.JPBS_142_17

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Aim: The aim of the study was to evaluate the serum lipid profile among untreated oral squamous cell carcinoma (OSCC) and oral submucous fibrosis (OSMF) patients. Materials and Methods: This study was done in three groups of patients - OSMF, OSCC, and control. There are twenty participants in each group. Calorimetric method using semi-autoanalyzer was used for analyzing the lipid levels (cholesterol, triglycerides [TGL], and high-density lipids [HDL]) after collecting 2 ml of fasting blood from these patients. Low-density lipid [LDL] values were obtained by calculator method. Results: There was a significant decrease in serum lipid levels of patients with OSMF and OSCC. Conclusion: The decrease in lipid levels in OSMF and OSCC patients is due to its utilization by the cells during the cancer process.

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