Journal of Pharmacy And Bioallied Sciences
Journal of Pharmacy And Bioallied Sciences Login  | Users Online: 2271  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 
    Home | About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions | Online submission


ORIGINAL ARTICLE
Year : 2017  |  Volume : 9  |  Issue : 5  |  Page : 237-240

Assessment of total antioxidant capacity and antimicrobial activity of Glycyrrhiza glabra in saliva of HIV-infected patients


1 Department of Public Health Dentistry, Mar Baselios Dental College, Kothamangalam, Kerala, India
2 Department of Pedodontics, Annoor Dental College and Hospital, Muvattupuzha, Kerala, India
3 Department of Prosthodontics, Mar Baselios Dental College, Kothamangalam, Kerala, India
4 Department of Oral and Maxillofacial Surgery, Annoor Dental College and Hospital, Muvattupuzha, Kerala, India
5 Department of Oral and Maxillofacial Surgery, Malabar Dental College and Research Center, Edappal, Kerala, India
6 Department of Orthodontics, Annoor Dental College and Hospital, Muvattupuzha, Kerala, India
7 Department of Public Health Dentistry, Indira Gandhi Institute of Dental Sciences, Pondicherry, India
8 Department of Public Health, Western University, Ontario, Canada

Correspondence Address:
Eby Aluckal
Department of Public Health Dentistry, Mar Baselios Dental College, Kothamangalam - 686 691, Kerala
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpbs.JPBS_141_17

Rights and Permissions

Objectives: The objectives of this study were to evaluate the antimicrobial activity and total antioxidant capacity (TAC) of licorice in Saliva of HIV/AIDS patients. Materials and Methods: Saliva specimens were collected from 20 people living with HIV infection, with CD4 count <500 cells/mm3 from people infected with HIV/AIDS in Mangalore city, India. A combination of amoxicillin-clavulanic acid and nystatin was taken as the positive control and normal saline as negative control. Results were compared using one-way analysis of variance followed by Tukey's post hoc analysis in SPSS 19. Results: The TAC was evaluated spectrophotometrically at 695nm using the phosphomolybdenum method. Glycyrrhiza glabra showed a statistically significant reduction (P < 0.05) in total Candida count. The TAC of G. glabra was found to be 4.467 mM/L. Conclusions: G. glabra extracts showed good anticandidal activity and also high antioxidant property which reduces the oxidative stress of HIV-infected people.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

suppl
 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2017    
    Printed22    
    Emailed0    
    PDF Downloaded88    
    Comments [Add]    
    Cited by others 1    

Recommend this journal