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ORIGINAL ARTICLE
Year : 2021  |  Volume : 13  |  Issue : 5  |  Page : 748-750

Assessment of c-reactive protein level in oral submucous fibrosis and oral squamous cell carcinoma patient


1 Department of Oral Pathology, Sarjug Dental College, Darbhanga, India
2 Department of Periodontics and Oral Implantology, Patna Dental College and Hospital, Bihar, India
3 Department of Conservative Dentistry and Endodontics, Shree Bankey Bihari Dental College, Ghaziabad, Uttar Pradesh, India
4 Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India
5 Department of Oral and Maxillofacial Surgery, I.T.S Dental College, Ghaziabad, Uttar Pradesh, India

Correspondence Address:
Geeta Sharma
Department of Oral Pathology, Sarjug Dental College, Darbhanga, Bihar
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpbs.JPBS_607_20

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Background: Potentially malignant disorders are highly prevalent in India. In this study, we assessed C-reactive protein (CRP) levels in patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC). Methodology: Sixty-four patients (OSMF and OSCC) were undertaken and were classified into 3 groups, OSMF patients (Group I, 34), OSCC (Group II, 30), and healthy controls (Group III, 26). Immunoturbidimetry method was used for the estimation of CRP levels. Results: Maximum cases in Group I was seen in the age group 40–60 years (males-10, females-3), Group II in the age group 40–60 years (males-11, females-5) and Group III (males-5, females-6). The mean CRP level in Group I was 6.12 ± 4.5 mg/l, in Group II was 28.4 ± 21.5 mg/l, and in Group III was 3.15 ± 2.19 mg/l. The difference was significant (P < 0.05). Conclusion: Authors found that OSMF and oral cancer patients had increased CRP levels as compared to healthy subjects.


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