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ORIGINAL ARTICLE
Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 1188-1192

Antimicrobial efficacy of green synthesis of silver nanoparticles against cariogenic pathogens – An In vitro study


1 Department of Conservative, Dentistry and Endodontics, Vivekanandha Dental College for Women, Namakkal, The TamilNadu Dr. M.G.R. Medical University, Tamil Nadu, India
2 Department of Conservative Dentistry and Endodontics, Rajah Muthiah Dental College, Annamalai University, Annamalai Nagar, Tamil Nadu, India

Correspondence Address:
M Chittrarasu
17/10, North Street, Poovalur (POST), Lalgudi (T.K), Tiruchirappalli - 621 712, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpbs.jpbs_338_21

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Background: Nowadays, emergence of drug resistance might happen in the world. Hence, invention of new dental material had started by researchers for the same. The present study evaluated the antimicrobial property of green synthesized nanosilver particles against dental cariogenic microorganisms such as Streptococcus mutans and Lactobacillus acidophilus. Materials and Methods: An in vitro study had been designed to meet the objectives. Galla Chinensis ellagic acid powder synthesized nanosilver particles (GCAgNPs) synthesized nanosilver particles were used in this study. The cariogenic bacteria S. mutans (ATCC 25175) and L. acidophilus (ATCC 4356) were used in this study. The antimicrobial activity was detected at different concentrations (1000 μg/ml, 500 μg/ml, 250 μg/ml, 125 μg/ml, and 62.5 μg/ml) by means of qualitative and quantitative methods. Results: The results show a statistically significant difference between all the concentration (1000 μg/ml, 500 μg/ml, 250 μg/ml, 125 μg/ml, 62.5 μg/ml) in Galla Chinensis synthesized silver nanoparticles (GCAgNPs) in S. mutans and L. acdiophilus. Intergroup comparison of GCAgNPs shows a statistically significant difference among all the concentrations against S. mutans and L. acidophilus. Conclusion: GCAgNPs show antimicrobial and antibiofilm activity against S. mutans and L. acidophilus microorganisms.


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