Journal of Pharmacy And Bioallied Sciences
Journal of Pharmacy And Bioallied Sciences Login  | Users Online: 6297  Print this pageEmail this pageSmall font sizeDefault font sizeIncrease font size 
    Home | About us | Editorial board | Search | Ahead of print | Current Issue | Past Issues | Instructions | Online submission

Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 1354-1359

To evaluate the role of positron emission tomography-computerized tomography in initial staging of carcinoma breast

1 MD (Radiotherapy), SMO, Community Health Centre, Sangat, Bathinda, India
2 Consultant, Department of Oncology, Onco Life Care Cancer Centre, Chiplun, Ratnagiri, Maharashtra, India
3 Intern (MBBS), GGS Medical College and Hospital, Faridkot, Punjab, India
4 Department of Radiation Oncology, GGS Medical College and Hospital, Faridkot, Punjab, India
5 Department of Radiation Oncology, ILBS, New Delhi, India
6 Department of Radiation Oncology, Government Medical College, Patiala, Punjab, India
7 Department of Radio-Diagnosis, GGS Medical College and Hospital, Faridkot, Punjab, India

Correspondence Address:
Manraj Singh Kang
Department of Radiation Oncology, GGS Medical College and Hospital, Faridkot, Punjab
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpbs.jpbs_163_21

Rights and Permissions

Background: Breast cancer is the most common cancer in urban and second common in rural Indian women. In India, in spite of the best treatment available being given to the patients they lose their lives because of paucity of diagnostic aids and lack of an organized breast cancer screening program. Early detection, accurate staging, and initiation of appropriate therapy are the key factors for improving the treatment outcome and prognosis of the disease for the patients. Traditional staging methods include clinical examination, blood tests, chest X-ray, ultrasound of the abdomen, and/or skeletal survey. As these tests lack sensitivity and specificity, these are being scaled down. The hybrid positron emission tomography-computerized tomography (PET-CT) is a unique tool in the field of imaging modalities that combines the effectiveness of PET and CT. This study was undertaken to assess the efficacy and accuracy of PET-CT as a single-session staging modality in the very initial stage itself and if it can replace the conventional means of staging. Methods: This was a cross-sectional study conducted in the Radiotherapy department at GGS Medical College and Hospital Faridkot from March 2014 to October 2015. 52 patients with newly diagnosed and histopathologically proven carcinoma breast were staged by conventional modalities (clinical examination, blood tests, X-ray chest, mammography, ultrasonography abdomen, skeletal survey) and by 18F-fluorodeoxyglucose (18F FDG) PET/CT. PET-CT images were used for the detection, localization, staging of tumors and detection, evaluation, and diagnosis of metastatic lesions, disease burden and organ function along with treatment planning and planning therapeutic procedures. Following the completion of initial study, the results of 18F FDG PET-CT staging in comparison with conventional staging method were assessed. Along with this, the accuracy, changes in staging of cases of carcinoma breast and cost-effectiveness of 18F-FDG PET-CT were also studied. Results: All the pathologic entities identified by conventional imaging were also perceived with 18F-FDG PET/CT. Therefore, we recommend the use of PET/CT as an important imaging modality for initial diagnosis of carcinoma breast.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal