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Year : 2021  |  Volume : 13  |  Issue : 6  |  Page : 1458-1461

Reliability of C-reactive protein as a biomarker for cardiovascular and oral diseases in young and old subjects

1 Department of Dentistry, All India Institute of Medical Sciences, Patna, Bihar, India
2 Department of Oral and Maxillofacial Pathology and Microbiology, ITS CDSR Dental College and Hospital, Ghaziabad, Uttar Pradesh, India
3 Department of Conservative Dentistry and Endodontics, Dr. B. R. Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India
4 Dental Officer, ECHS Polyclinic station HQ, Gopalpur, Cantonment, Odisha, India
5 Department of Dentistry, Sarjug Dental College and Hospital, Darbhanga, Bihar, India

Correspondence Address:
Swati Priya
Department of Conservative Dentistry and Endodontics, Dr. B. R. Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jpbs.jpbs_251_21

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Background: Increased C-reactive protein (CRP) levels are associated with various diseases such as cardiovascular diseases (CVDs), periodontal diseases, and other inflammatory diseases and can be an effective biomarker for predicting future risks of periodontal diseases. Aims: The present trial was carried out to evaluate if CRP levels are lower in healthy and young individuals as compared to individuals with high body mass index (BMI), gingival index, and CVDs by assessing CRP levels in young and old individuals (more than 45 years). Materials and Methods: A total of 174 participants were recruited for the study and were divided into three following groups: Less than 45 years healthy participants (n = 124), more than 45 years healthy participants, and more 45-year-old participants with CVDs (n = 25). The collected data were subjected to the statistical analysis. Results: In Group I, females had a CRP level of 8476 ± 6.86 pg, females of Group II had a CRP value of 13,262 ± 3.76, and in females of Group III CRP value was 22,761 ± 6.24 pg. These values, respectively, for males were 8494 ± 7.68, 13,840 ± 4.82, and 13,839 ± 3.8. In smokers, the CRP values for Group I, II, and III were 29,012 ± 14.66, 12,568 ± 4.16, and 16,826 ± 3.42, respectively. Conclusion: CRP levels were higher in males as compared to females. Higher BMI was associated with higher values of CRP. The participants with higher BMI presented higher CRP values irrespective of age.

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