Year : 2011 | Volume
: 3 | Issue : 2 | Page : 226--229
In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L.
Anju Dhiman1, Arun Nanda1, Sayeed Ahmad2, B Narasimhan1
1 Department of Pharmaceutical Sciences, M.D. University, Rohtak, Haryana, India
2 Department of Pharmacognosy and Phytochemistry, Bioactive Natural Product Laboratory, Faculty of Pharmacy, Jamia Hamdard, New Delhi, India
Aim: This study was designed to examine the chemical composition and in vitro antimicrobial potential of methanolic extract of Psidium guajava Linn (Myrtaceae). Materials and Methods: The inhibitory effect of methanolic extract of P. guajava was tested against three bacterial and two fungal strains by using the paper disc diffusion method. Results: The methanolic extract exhibited antibacterial activity against E. coli with minimum inhibitory concentration, 0.78 μg/ml, minimum bactericidal concentration of 50 μg/ml, and appreciable antifungal activity with minimum inhibitory concentration of 12.5 μg/ml. Preliminary phytochemical analysis of methanolic extract revealed the presence of antimicrobial compounds such as flavonoids, steroids, and tannins, which may contribute for the antimicrobial action of P. guajava. Conclusion: The extract was found to be bacteriostatic and fungistatic in action.
Department of Pharmaceutical Sciences, M.D. University, Rohtak, Haryana
|How to cite this article:|
Dhiman A, Nanda A, Ahmad S, Narasimhan B. In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L. J Pharm Bioall Sci 2011;3:226-229
|How to cite this URL:|
Dhiman A, Nanda A, Ahmad S, Narasimhan B. In vitro antimicrobial activity of methanolic leaf extract of Psidium guajava L. J Pharm Bioall Sci [serial online] 2011 [cited 2021 Jan 18 ];3:226-229
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=2;spage=226;epage=229;aulast=Dhiman;type=0