Journal of Pharmacy And Bioallied Sciences

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Year
: 2012  |  Volume : 4  |  Issue : 5  |  Page : 114--115

Preparation and evaluation of cilnidipine microemulsion


Hemal Tandel, Krunal Raval, Anil Nayani, Manish Upadhay 
 The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara, India

Correspondence Address:
Hemal Tandel
The Maharaja Sayajirao University of Baroda, Kalabhavan, Vadodara
India

Cilnidipine, a calcium channel blocker having neuroprotective action and BCS Class II drug, hence formulating in Microemulsion will increase solubility, absorption and bioavailability. The formulation was prepared using titration method by tocotrienol, tween 20 and transcutol HP as oil, surfactant and co-surfactant and characterized for dilutability, dye solubility, assay (98.39±0.06), pH (6.6±1.5), Viscosity (98±1.0 cps) and Conductivity (0.2±0.09 μS/cm). The formulation was optimized on basis of percentage transmittance (99.269±0.23 at 700 nm), Globule size (13.31±4.3 nm) and zeta potential (-11.4±2.3 mV). Cilnidipine microemulsion was found to be stable for 3 months.


How to cite this article:
Tandel H, Raval K, Nayani A, Upadhay M. Preparation and evaluation of cilnidipine microemulsion.J Pharm Bioall Sci 2012;4:114-115


How to cite this URL:
Tandel H, Raval K, Nayani A, Upadhay M. Preparation and evaluation of cilnidipine microemulsion. J Pharm Bioall Sci [serial online] 2012 [cited 2022 Jun 30 ];4:114-115
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=5;spage=114;epage=115;aulast=Tandel;type=0