Journal of Pharmacy And Bioallied Sciences

SYMPOSIUM - HERBAL DRUGS AND BOTANICALS - RESEARCH ARTICLES
Year
: 2015  |  Volume : 7  |  Issue : 4  |  Page : 300--303

Antimicrobial activity of aqueous and organic extracts of a Saudi medicinal plant: Rumex nervosus


Abdul Rahman K Al-Asmari1, Yunus M Siddiqui1, Md Tanwir Athar1, Ahmed Al-Buraidi2, AS Al-Eid3, Ghalib B Horaib4 
1 Department of Research, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia
2 Department of ENT, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia
3 Department of Research,Pharmacy, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia
4 Department of Dermatology, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia, Kingdom of Saudi Arabia

Correspondence Address:
Abdul Rahman K Al-Asmari
Department of Research, Prince Sultan Military Medical City, Riyadh
Kingdom of Saudi Arabia

Objective: The antimicrobial effect of aerial part of Rumex nervosus obtained from the Southern region of Saudi Arabia was evaluated on bacterial strains Staphylococcus aureus, methicillin resistant S. aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas Aeruginosa, and fungal strain Candida albicans. Materials and Methods: The solvents used for the extraction were aqueous, hexane, and methanol. The in vitro antimicrobial activity was performed by agar diffusion and disk diffusion methods and the confirmation of this activity was done by the enumeration of colony forming units (CFU). Results: The aqueous extract showed the growth inhibitory effect on Gram-positive bacteria while the Gram-negative P. aeruginosa was the most sensitive microorganism as determined by the agar diffusion technique. Surprisingly, the extract showed little antibacterial activity on other Gram-negative bacteria (E. coli) by this technique. Ethanolic extract was also found to be inhibitory to the growth of microorganisms. Hexane extract was relatively low in antimicrobial activity on Gram-negative E. coli and P. aeruginosa, while both the organic extracts were inhibitory to the growth of the fungus, C. albicans. Hexane gave no conclusive results with agar or disk diffusion methods, but showed the microbial growth inhibition in CFU enumeration. The antibacterial activity of active extracts was compared with vancomycin while antifungal activity of was compared with amphotericin B. Conclusion: The results obtained in the present study suggest that R. nervosus showed a marked antimicrobial activity with the test organisms.


How to cite this article:
Al-Asmari AK, Siddiqui YM, Athar MT, Al-Buraidi A, Al-Eid A S, Horaib GB. Antimicrobial activity of aqueous and organic extracts of a Saudi medicinal plant: Rumex nervosus.J Pharm Bioall Sci 2015;7:300-303


How to cite this URL:
Al-Asmari AK, Siddiqui YM, Athar MT, Al-Buraidi A, Al-Eid A S, Horaib GB. Antimicrobial activity of aqueous and organic extracts of a Saudi medicinal plant: Rumex nervosus. J Pharm Bioall Sci [serial online] 2015 [cited 2020 Nov 28 ];7:300-303
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2015;volume=7;issue=4;spage=300;epage=303;aulast=Al-Asmari;type=0