Journal of Pharmacy And Bioallied Sciences

: 2015  |  Volume : 7  |  Issue : 5  |  Page : 26--31

Macrolide resistance in Streptococcus species

A Ilakkiya1, Shabana Parveen2, C Naveen Kumar1, S Swathi3 
1 Department of Microbiology, Madha Medical College, Chennai, Tamil Nadu, India
2 Department of Microbiology, SRM Medical College, Chennai, Tamil Nadu, India
3 Department of Microbiology, Sri Lakshmi Narayana Institute of Medical Sciences, Affiliated to Bharath University, Puducherry, India

Correspondence Address:
C Naveen Kumar
Department of Microbiology, Madha Medical College, Chennai, Tamil Nadu

Background: The Streptococci are Gram-positive spherical bacteria (cocci) that characteristically form pairs and chains during growth. Some macrolide-resistant bacteria lack the proper receptor on the ribosome (through methylation of the rRNA). This may be under plasmid or chromosomal control. Aim and Objectives: The aim was to study the prevalence of macrolide resistance among the isolate and evaluate the degree of resistance by minimum inhibitory concentration (MIC) method. And also to detect the phenotypic pattern of macrolide resistance. Materials and Methods: All age group attending general medicine OPD and pediatric OPD with symptoms of respiratory and pyogenic infections are included in the study. Various samples are collected with detailed case history and processed for macrolide resistance among beta hemolytic Streptococci MIC method and D-test. Results: According to our studies resistance pattern in Group A Streptococci by D-test, cMLS was 27.85%, iMLS was 13.92%, M-type was 55.69%, in GCS, cMLS was 17.6%, M-type was 82.35% In GGS, cMLS was 31.58%, iMLS was 10.53% and M-type was 57.89%. Conclusions: Therefore by this study, we would like to highlight the necessity to do antibiotic sensitivity testing for all isolates, and limit the usage of antibiotics, whenever necessary and select the appropriate antibiotics for resistant strains.

How to cite this article:
Ilakkiya A, Parveen S, Kumar C N, Swathi S. Macrolide resistance in Streptococcus species.J Pharm Bioall Sci 2015;7:26-31

How to cite this URL:
Ilakkiya A, Parveen S, Kumar C N, Swathi S. Macrolide resistance in Streptococcus species. J Pharm Bioall Sci [serial online] 2015 [cited 2021 Jan 25 ];7:26-31
Available from:;year=2015;volume=7;issue=5;spage=26;epage=31;aulast=Ilakkiya;type=0