Journal of Pharmacy And Bioallied Sciences

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 9  |  Issue : 5  |  Page : 112--116

Effect of fluoride varnish and dentifrices and its combination on deciduous enamel demineralization: An In vitro study


Allama Prabhu1, BG Prasanna2, B Sakeenabhi1, GM Prashanth1, R Subramaniam3, Mallikarjuna Ragher4 
1 Department of Public Health Dentistry, College of Dental Sciences, Davanagere, Karnataka, India
2 Department of Prosthodontics, College of Dental Sciences, Davanagere, Karnataka, India
3 Department of Public Health Dentistry, Indira Gandhi Institute of Dental Sciences, Kothamangalam, Kerala, India
4 Department of Prosthodontics, Yenepoya Dental College, Yenepoya University, Mangalore, Karnataka, India

Correspondence Address:
Allama Prabhu
Department of Public Health Dentistry, College of Dental Sciences, Davanagere - 577 002, Karnataka
India

Introduction: Dental caries remains the most important dental health problem in developing countries. Application of varnish on tooth surfaces is shown to promote the uptake of firmly bound fluoride by enamel, which is considered important. Along with the incorporation of fluoride into the crystalline lattice, there is formation of calcium fluoride compounds on enamel. Methodology: Seventy deciduous canines were covered with nail polish. A window measuring 4 mm × 4 mm was left on their buccal surface, These were randomly assigned to seven groups (n = 6): S: sound enamel not subjected to any regimen or treatment; N: negative control, subjected to the pH-cycling regimen without any treatment; D1 and D2: subjected to the pH-cycling regimen and treated two times daily with 1100 and 500 ppm F dentifrice, respectively; VF: fluoride varnish (subjected to F-varnish before and in the middle of the pH-cycling regimen); and VF + D1 and VF + D2. After a period of 10 days, sectioning of teeth was done, and enamel demineralization was measured. Results: The combination of dentifrice and varnish (groups VF + D1 and VF + D2) significantly reduced demineralization compared with the N group at all distances evaluated (P < 0.05), but the combination did not differ from the dentifrice groups at most distances from the surface (P > 0.05). Conclusion: The results of this study suggest that the combination of F-varnish with dentifrices containing 500 or 1100 ppm F is not more effective in reducing demineralization in primary teeth than the isolated effect of dentifrice containing 1100 ppm.


How to cite this article:
Prabhu A, Prasanna B G, Sakeenabhi B, Prashanth G M, Subramaniam R, Ragher M. Effect of fluoride varnish and dentifrices and its combination on deciduous enamel demineralization: An In vitro study.J Pharm Bioall Sci 2017;9:112-116


How to cite this URL:
Prabhu A, Prasanna B G, Sakeenabhi B, Prashanth G M, Subramaniam R, Ragher M. Effect of fluoride varnish and dentifrices and its combination on deciduous enamel demineralization: An In vitro study. J Pharm Bioall Sci [serial online] 2017 [cited 2022 Aug 16 ];9:112-116
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2017;volume=9;issue=5;spage=112;epage=116;aulast=Prabhu;type=0