Journal of Pharmacy And Bioallied Sciences

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 12  |  Issue : 5  |  Page : 308--312

Assessment of salivary flow rate in patients with chronic periodontitis


Chitra G Vallabhan1, Sujith Sivarajan2, Ashwin Devanarayanan Shivkumar3, Vandana Narayanan3, Steffi Vijayakumar1, RS Indhuja1 
1 Department of Periodontology, Sree Mookambika Institute of Dental Sciences, Kulashekaram, Tamil Nadu, India
2 Department of Orthodontics and Dentofacial Orthopedics, PMS College of Dental Science and Research, Thiruvananthapuram, Kerala, India
3 Department of Prosthodontics, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India

Correspondence Address:
Chitra G Vallabhan
Department of Periodontology, Sree Mookambika Institute of Dental Sciences, Kulashekaram, Tamil Nadu.
India

Background: Chronic periodontitis (CP) is an infectious disease, primarily affecting the attachment apparatus of the dentition, and is categorized into mild, moderate, and severe periodontitis on the basis of its severity. It is a well-established and proven fact that an adequate level of saliva is essential for maintaining the integrity of oral tissues including the periodontium. Although various factors, such as stimulation, circadian rhythm, diet, age, and drugs, can affect the salivary flow rate, many recent studies have provided evidence that it can be altered by pathological inflammatory conditions such as periodontal diseases. Therefore, this study has been undertaken to assess the unstimulated and stimulated salivary flow rate in the different clinical stages of chronic periodontitis. Materials and Methods: This study comprised 60 study participants, who were divided into four groups depending on clinical attachment level (CAL). In all, both unstimulated and stimulated saliva were collected, and the flow rate was expressed in milliliter per minute. Results: Statistical analysis was accomplished with Statistical Package for the Social Sciences (SPSS) software. One-way analysis of variance (ANOVA) was used to analyze differences in salivary flow rate among the groups. Statistical significance was set at P < 0.05. The amount of unstimulated saliva in healthy subjects, in mild, moderate, and severe periodontitis was 0.766, 0.400, 0.270, and 0.146 mL/min, respectively. Likewise, the amount of stimulated saliva in healthy subjects, in mild, moderate, and severe periodontitis was 1.017, 0.494, 0.347, and 0.236 mL/min, respectively. Conclusion: The study identified a significant decrease in both unstimulated and stimulated salivary flow rate with the severity of progression of chronic periodontitis.


How to cite this article:
Vallabhan CG, Sivarajan S, Shivkumar AD, Narayanan V, Vijayakumar S, Indhuja R S. Assessment of salivary flow rate in patients with chronic periodontitis.J Pharm Bioall Sci 2020;12:308-312


How to cite this URL:
Vallabhan CG, Sivarajan S, Shivkumar AD, Narayanan V, Vijayakumar S, Indhuja R S. Assessment of salivary flow rate in patients with chronic periodontitis. J Pharm Bioall Sci [serial online] 2020 [cited 2020 Oct 23 ];12:308-312
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2020;volume=12;issue=5;spage=308;epage=312;aulast=Vallabhan;type=0