Journal of Pharmacy And Bioallied Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 13  |  Issue : 5  |  Page : 120--123

Evaluation of preoperative salivary cortisol level in patients undergoing major maxillofacial surgery


Archana Kumari1, Praveen Chandra2, Sonali Roy3, Ritika Agarwal4, Aartika Singh5, Suprabha Sharan6 
1 Department of Dentistry, VIMS Pawapuri (Nalanda), Patna, Bihar, India
2 Department of Prosthodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India
3 Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India
4 Department of Dentistry, Patna Medical College and Hospital, Bihar, India
5 Department of Orthodontics and Dentofacial Orthopedics, School of Dental Sciences, Sharda University Greater Noida, Uttar Pradesh, India
6 Private Practitioner, Patna, Bihar, India

Correspondence Address:
Sonali Roy
Department of Dentistry, Nalanda Medical College and Hospital, Patna - 800020, Bihar
India

Aim: The main purpose of the study was to compare the preoperative salivary cortisol levels 3 days before the major surgery under general anesthesia and to compare it with the patients undergoing extraction under local anesthesia. Materials and Methods: Forty-two patients were undergoing major surgery and 42 age- and sex-matched patients undergoing dental extraction were included and their salivary cortisol levels were analyzed before and after the dental procedure. Results: Results showed that there is a significant increase in the mean salivary cortisol concentration after extraction (23.7 ± 9.2) than before extraction (18.9 ± 23.7) in the study group (P = 0.015) as well as in the control group. The comparison between salivary cortisol in the study group before (18.9 ± 23.7) and after (23.7 ± 9.2) surgery was significantly higher than the control group (15.2 ± 5.5) (P = 0.013 and 0.005), respectively. Conclusion: We have concluded from this study that the salivary cortisol level shows a significant increase on the day of surgery.


How to cite this article:
Kumari A, Chandra P, Roy S, Agarwal R, Singh A, Sharan S. Evaluation of preoperative salivary cortisol level in patients undergoing major maxillofacial surgery.J Pharm Bioall Sci 2021;13:120-123


How to cite this URL:
Kumari A, Chandra P, Roy S, Agarwal R, Singh A, Sharan S. Evaluation of preoperative salivary cortisol level in patients undergoing major maxillofacial surgery. J Pharm Bioall Sci [serial online] 2021 [cited 2022 Jul 3 ];13:120-123
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=120;epage=123;aulast=Kumari;type=0