Journal of Pharmacy And Bioallied Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 13  |  Issue : 5  |  Page : 212--216

Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study


Nutan Mala1, Sinha Sonal2, Amit Kumar3, Harsh Vardhan Choudhary4, Prafulla Songara5, Kumar Ramesh6 
1 Department of Conservative Dentistry and Endodontics, Buddha Institute of Dental Science and Hospital, Patna, Bihar, India
2 Department of Conservative Dentistry and Endodontics, Dr. B. R. Ambedkar Institute of Dental Sciences and Hospital, Patna, Bihar, India
3 Department of Conservative Dentistry and Endodontics, Mithila Minority Dental College, Darbhanga, Bihar, India
4 Dental Surgeon, Public Health Centre, Parwalpur, Nalanda, Bihar, India
5 Department of Microbiology, Government Medical College, Ratlam, Madhya Pradesh, India
6 Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India

Correspondence Address:
Prafulla Songara
Department Of Microbiology, Government Medical College, Ratlam, Madhya Pradesh
India

Background: Dental caries is a chronic, widespread, and infectious disease affecting the large population. Anticariogenic effects of different herbs and natural products are observed, cinnamon among these, showed the ability to inhibit Streptococcus mutans biofilm. Objectives: The aim of this study was to assess the cinnamon water extract use on nicotine exposed S. mutans biolfilms. Materials and Methods: Microtiter plates having S. mutans culture were treated using varying nicotine concentration range (0–32 mg/ml). These were then either subjected to cinnamon water (2.5 mg/ml) extract or no treatment and analyzed using a spectrophotometer to see planktonic growth, total growth absorbance, and biofilm formation. Results: About 2.5 mg/ml of cinnamon water inhibits the S. mutans biofilm (nicotine-induced) considerably at various nicotine levels (0–32 mg/ml). Conclusion: Cinnamon water extract has a powerful inhibitory effect for S. mutans growth. Nicotine-induced S. mutans growth is markedly reduced by treating with cinnamon water extract.


How to cite this article:
Mala N, Sonal S, Kumar A, Choudhary HV, Songara P, Ramesh K. Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study.J Pharm Bioall Sci 2021;13:212-216


How to cite this URL:
Mala N, Sonal S, Kumar A, Choudhary HV, Songara P, Ramesh K. Cariostatic efficacy of cinnamon water extract on Streptococcus mutans: An In vitro study. J Pharm Bioall Sci [serial online] 2021 [cited 2021 Jul 29 ];13:212-216
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=212;epage=216;aulast=Mala;type=0