Journal of Pharmacy And Bioallied Sciences

REVIEW ARTICLE
Year
: 2021  |  Volume : 13  |  Issue : 5  |  Page : 6--10

Fibroblastic growth factor as a diagnostic and prognostic marker in odontogenic cysts and tumors: A systematic review


Gururaj Narayana Rao1, Adlin Saroja Rosaian1, Gowthami Jawahar1, P Hari Nivas Raj1, J Beryl Rachel1, P Blessing Emmanuel2 
1 Department of Oral and Maxillofacial Pathology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu, India
2 Peterson Dental Clinic, Tenkasi District, Tamil Nadu, India

Correspondence Address:
Gururaj Narayana Rao
Department of Oral and Maxillofacial Pathology, CSI College of Dental Sciences and Research, Madurai, Tamil Nadu
India

Cellular signaling proteins maintain the basic activities of cell and communication, between the cells for normal growth and development and pathological situation as well. Fibroblast growth factor (FGF) and fibroblast growth factor receptors (FGFRs) have a comparatively huge part to play in the cellular communication processes. Human FGF has 22 members, 18 ligands, and 4 tyrosine kinase receptors for binding and is expressed in a wide range of cells. Any alteration in these factors would disrupt their normal function, leading to various abnormalities. The aim of this systematic analysis, is to understand the FGFs, the physiological and pathological role of FGF in oral diseases, and to predict the use of FGF in the predilection toward odontogenic cyst and tumors. This review helps confer the role of FGF in various physiological and pathological aspects in systemic diseases and analyzes its role in diagnosis and prognosis of odontogenic cysts and tumors.


How to cite this article:
Rao GN, Rosaian AS, Jawahar G, Raj P H, Rachel J B, Emmanuel P B. Fibroblastic growth factor as a diagnostic and prognostic marker in odontogenic cysts and tumors: A systematic review.J Pharm Bioall Sci 2021;13:6-10


How to cite this URL:
Rao GN, Rosaian AS, Jawahar G, Raj P H, Rachel J B, Emmanuel P B. Fibroblastic growth factor as a diagnostic and prognostic marker in odontogenic cysts and tumors: A systematic review. J Pharm Bioall Sci [serial online] 2021 [cited 2021 Jun 22 ];13:6-10
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=6;epage=10;aulast=Rao;type=0