Journal of Pharmacy And Bioallied Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 13  |  Issue : 5  |  Page : 748--750

Assessment of c-reactive protein level in oral submucous fibrosis and oral squamous cell carcinoma patient


Geeta Sharma1, Randhir Kumar2, Sharib Abdus Salam2, Prashant Bhasin3, Nishant Kumar Tewari4, Suman Yadav5 
1 Department of Oral Pathology, Sarjug Dental College, Darbhanga, India
2 Department of Periodontics and Oral Implantology, Patna Dental College and Hospital, Bihar, India
3 Department of Conservative Dentistry and Endodontics, Shree Bankey Bihari Dental College, Ghaziabad, Uttar Pradesh, India
4 Department of Dentistry, Nalanda Medical College and Hospital, Patna, Bihar, India
5 Department of Oral and Maxillofacial Surgery, I.T.S Dental College, Ghaziabad, Uttar Pradesh, India

Correspondence Address:
Geeta Sharma
Department of Oral Pathology, Sarjug Dental College, Darbhanga, Bihar
India

Background: Potentially malignant disorders are highly prevalent in India. In this study, we assessed C-reactive protein (CRP) levels in patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC). Methodology: Sixty-four patients (OSMF and OSCC) were undertaken and were classified into 3 groups, OSMF patients (Group I, 34), OSCC (Group II, 30), and healthy controls (Group III, 26). Immunoturbidimetry method was used for the estimation of CRP levels. Results: Maximum cases in Group I was seen in the age group 40–60 years (males-10, females-3), Group II in the age group 40–60 years (males-11, females-5) and Group III (males-5, females-6). The mean CRP level in Group I was 6.12 ± 4.5 mg/l, in Group II was 28.4 ± 21.5 mg/l, and in Group III was 3.15 ± 2.19 mg/l. The difference was significant (P < 0.05). Conclusion: Authors found that OSMF and oral cancer patients had increased CRP levels as compared to healthy subjects.


How to cite this article:
Sharma G, Kumar R, Salam SA, Bhasin P, Tewari NK, Yadav S. Assessment of c-reactive protein level in oral submucous fibrosis and oral squamous cell carcinoma patient.J Pharm Bioall Sci 2021;13:748-750


How to cite this URL:
Sharma G, Kumar R, Salam SA, Bhasin P, Tewari NK, Yadav S. Assessment of c-reactive protein level in oral submucous fibrosis and oral squamous cell carcinoma patient. J Pharm Bioall Sci [serial online] 2021 [cited 2021 Sep 19 ];13:748-750
Available from: https://www.jpbsonline.org/article.asp?issn=0975-7406;year=2021;volume=13;issue=5;spage=748;epage=750;aulast=Sharma;type=0