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  Indian J Med Microbiol
 

Figure 3: Effect of HLE (30-300 mg/kg, p.o.) and morphine (1-10 mg/kg, i.p.) on the time course curves (a and c) and the AUC (b and d) of the formalin test in mice. Nociceptive scores are shown in 5-min time blocks up to 60 min following formalin injection for the time course curves. Values are means ± SEM (n=5). *P<0.05, **P<0.01, and ***P<0.001 compared to the vehicle-treated group (two-way ANOVA followed by Bonferroni's post hoc test). †††P <0.001 compared to the vehicle-treated (control) group (one-way ANOVA followed by the Newman-Keuls post hoc test)

Figure 3: Effect of HLE (30-300 mg/kg, p.o.) and morphine (1-10 mg/kg, i.p.) on the time course curves (a and c) and the AUC (b and d) of the formalin test in mice. Nociceptive scores are shown in 5-min time blocks up to 60 min following formalin injection for the time course curves. Values are means ± SEM (n=5). *P<0.05, **P<0.01, and ***P<0.001 compared to the vehicle-treated group (two-way ANOVA followed by Bonferroni's post hoc test). †††P <0.001 compared to the vehicle-treated (control) group (one-way ANOVA followed by the Newman-Keuls post hoc test)